5 Strange Medical Conditions You Have Never Heard Of

You have probably heard of many diseases and health problems that affect humans, but there are some strange syndromes out there that you probably do not know about. How many of these unusual medical conditions have you heard of?

Concept of anger frustration outburst head

Explosive Head Syndrome is a strange sleep disorder where people hear a loud noise or explosion in their head.

Explosive head syndrome

Imagine for a second you were transposed into the karmic driven world of Earl. No, you have not been shot. you have explosive head syndrome. This strange condition, also known as hypnotic or “explosive” sleep disorder, is a rare condition in which a sufferer hears loud noises in the head. The most common time these noises occur is when you fall asleep. Noises can range from lightning to gunfire, but the sounds can be strange, such as creaking doors. In most cases, the sound will only last a few seconds, but may be more persistent and be associated with other symptoms, such as the appearance of a flashing light.

Explosive head syndrome is more common in women over the age of 50 who are anxious or tired, but it also occurs in young adults. According to the Cleveland Clinic, 16% of college students reported it in a study. It’s not dangerous – although it can be scary for those who experience it. Unfortunately, researchers still do not understand why some people experience this and others do not.

Germany concept

Foreign accent syndrome was first described in a Norwegian woman who was hit in the head by a bomb fragment during World War II and took on a strong German accent.

Foreign accent syndrome

Foreign accent syndrome (FAS) is a condition in which a person speaks with a different accent. Suddenly, you sound like you are from another country. Some people with this syndrome have another condition, such as a brain tumor or multiple sclerosis, but there has been at least one case of a woman developing it after dental surgery. Although rare, there is no cure. The treatment most doctors recommend is speech therapy to correct pronunciation.

A neurologist in Norway first described the condition in 1941. A Norwegian woman was struck by a bomb during World War II and began to speak with a strong German accent. So strong was the accent that it became the target of hate speech against the Germans. Since then, the disease has been documented throughout Europe and North America, including in people born and raised in the United States.

Tree Man

Abul Bajandar, 25, is the fourth man in the world with tree disease, a rare skin disorder caused by a virus called human papillomavirus, and is awaiting treatment at Dhaka Medical College in Dhaka, Bangladesh. Credit: Monirul Alam

Tree Man disease

Tree Man disease, also known as epidermodysplasia verruciformis, causes a type of viral wart to develop throughout the body. Warts are not contagious and doctors can remove them with surgery, but they tend to come back. In addition, warts are associated with a higher risk of skin cancers (cancers that affect the skin). This disorder usually occurs in families.

Interestingly, people with tree disease have problems regulating the amount of zinc in cells, including viral cells. There is no cure for this condition, so if you think you may have it, your best bet is to see a dermatologist as soon as possible.

Sasupan supra

Supatra “Nat” Sasuphan from Thailand was born with hair loss or “werewolf syndrome”. Credit: guinnessworldrecords.com

Human werewolf syndrome

Here’s a genetic disorder you’ve probably never heard of: human werewolf syndrome, also known as hair loss. This condition, discovered in 1600, causes the growth of abundant hair on a person’s face and body. It affects all races and sexes, it is so rare that there are only about 50 known cases in the world. Some people with the disease have hair all over their body and look like werewolves. Other people with this rare condition only have thick patches on their face or other discrete areas of skin.

Human werewolf syndrome can occur at birth or develop later in life. It is usually harmless, but sometimes the extra hairs cause irritation or discomfort if the wounds become open or tangled in clothes or jewelry. Otherwise, people with human werewolf syndrome show good health and do not shorten their lifespan.

Alice in Wonderland concept

People with the neurological condition known as Alice in Wonderland Syndrome may perceive objects as smaller than they actually are.

Alice in Wonderland’s syndrome

Alice in Wonderland syndrome is a rare neurological condition that affects the sense of time, body image, sound and size of the person. It takes its name from Lewis Carroll’s novel, and is also referred to as Todd Syndrome, dwarf delusions and microscopy. The disease usually occurs in young children or in people with brain damage. Symptoms are hallucinations or distortions of perception (such as seeing objects smaller than they actually are).

An example would be a child who suddenly thinks that objects are smaller in size or farther than they are. They may also have a distorted body image, believing that their body is smaller than it is. People with Alice in Wonderland syndrome often have migraine headaches and the condition is sometimes associated with tumors in the brain. There is no cure for this condition other than controlling migraine headaches.

Severe itching

People who suffer from watery itching have intense itching after contact with water.

Aquagenic Pruritus

Watery itching is a rare skin condition that causes intense itching after contact with water. It can occur in people with or without other skin conditions, but is more common in people with[{” attribute=””>eczema or other rashes.

The itching usually begins within 5-10 minutes of contact with water and can be severe, so much so that the person is unable to sleep. The symptoms can last for hours and may require antihistamines to manage the irritation. Some people develop such distressing itching that they become afraid to take a bath. However, bathing in cold water can sometimes temporarily stop the itching.

The Bottom Line

There you have it; some bizarre and, thankfully, rare conditions that cause strange symptoms. Needless to say, you probably don’t want any of them!


  1. My.ClevelandClinic.org. “Exploding Head Syndrome”
  2. ABCNews.go.com. “Rare Syndrome Causes Woman to Speak with a Foreign Accent”
  3. Healthline.com. “Hypertrichosis (Werewolf Syndrome): Causes, Treatments, and Types”
  4. Emedicine.medcape.com. “Congenital Hypertrichosis Lanuginosa
  5. CPNeurology.org. “Alice in Wonderland Syndrome”
  6. My.ClevelandClinic.org “Aquagenic Pruritis: Causes, Symptoms, and Treatment”

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